Twenty-four male lambs (Rambouillet 23.5 kg � 3.17 kg initial BW) were fed a basal diet with treatments which consisted of a control and oral doses of ruminally-protected choline (4 g/d RPC) and plant-based choline (4 g/d Biocholine) in a completely randomized design with initial weight as a covariate. The experiment was conducted for 42 days during which live weight, dry matter intake, carcass characteristics, blood metabolites and basic hemograms were measured. The daily gain in lambs was similar between treatments. Intake was higher in lambs given Biocholine (1.32 kg/d). The L value and mineral content in the meat were improved with both sources of choline. Blood triglycerides increased by RPC compared with the other treatments, and cholesterol was reduced by Biocholine. Alanine transaminase (ALT) and aspartate aminotransferase (AST) activity decreased by effect of choline. Hematological parameters were affected by choline supplementation regardless of the source; erythrocyte, monocytes and lymphocytes count decreased with both sources of choline in growing lambs.
The aim of this study is to introduce an application that enables information sharing and communication between visually-impaired individuals and able-bodied. For the purposes of the study, web-based audio library automation was designed and the usability of the system was analyzed regarding the volunteers who record audio books and the visually-impaired individuals. The visually-impaired individuals who took part in the test procedures in order to make a general evaluation of the system reported that the system was theoretically necessary and successful. As for the usability aspect, positive comments were received regarding the automation system developed. The authors believe that the current study is likely to be an alternative reference source for the related literature and further research studies to be conducted in the field.
Automated segmentation of white matter (WM) and gray matter (GM) is a very important task for detecting multiple diseases. The paper proposes a simple method for WM and GM extraction form magnetic resonance imaging (MRI) of brain. The proposed method is based on binarization, wavelet decomposition, and convexhull and produce very effective results in the context of visual inspection and as well as quantifiably. It is tested on three different (Transvers, Sagittal, Coronal) types of MRI of brain image and the validation of experiment indicate that an accurate detection and segmentation of the interesting structures or particular region of MRI of brain image.
This study was designed to develop a reversible middle cerebral artery (MCA) occlusion/reperfusion model in monkeys.\nBy inserting a Cordis steerable guidewires balloon catheter (595-E014) from the femoral artery of 12 male adult monkeys (Macaca mulatta) weighting 5.5±0.5Kg, the balloon catheter could be inserted into the MCA and occluded the blood flow. Magnetic resonance T1, T2 and DWI showed ischemic signals in MCA supplied area. Neurological evaluation demonstrated neurological deficits in the ischemic group. Neuropathological examinations were consistent with the neurological evaluations. The results suggested that this monkey MCAO model seemed close to human stroke.
Abstract\nIntroduction: Infertility is a problem that in addition to psychological effects, its high medical costs is also gripped the family and society. Regarding the role of the hormone oxytocin in stimulating ovulation and its less complications and cost, it may be considered substitutes for HCG. We decided to perform this study because the mechanism of effect of oxytocin on ovulation is not clear and no study has been conducted directly about its effect on LH surge. Methods: Of infertile women without ovulation, presenting to Iran North-West Gynecology specialized clinics, which had ovulation following excitation with Clomiphene, 200 patients were selected, and 200 patients received 5 U intra-muscular oxytocin. This was \"experimental\" and \"Case- Control\" study in which the subgroups were cased for: ultrasound study of follicular growth and follicle diameter measurement; serum LH levels measured periodically in both groups; Ovulation confirming using serum progesterone measurement in the middle of the luteal phase. The data obtained in the groups were analyzed by SPSS software version 15 using T-test. Results: The mean serum LH levels after 24 h was 21.87±21.71 mIu/ml in Control group and 23.77±34.51 mIu/ml in Case group, without significant difference (p=0.836); but U-Man- Whitney test showed significant difference (p=0.029) of mid-luteal average serum progesterone between the Control and Case groups (15.92 ng/ml and 23.88 ng/ml respectively). Conclusion: Although there was not significant difference in the mean serum LH after 24 h in two groups, but the presence of significant difference in mean mid- luteal progesterone levels in both groups suggest that administration of oxytocin is effective in the Ovulation induction.
The textile wastewater with the dye is released in various ways into the environment and it cause significant environmental problems. Due to the stability of modern dyes, conventional biological treatment methods for industrial wastewater are ineffective, resulting in an intensively colored discharge from the treatment facilities. Thus, there is a need for developing treatment methods that is more effective in eliminating dyes from the waste stream at its source. The most effective methods of dye removal from wastewater are adsorption and the use of enzymes. In this study, removal of Acid red 37 from aqueous solutions has been studied using silica fume waste material after its modification with laccase from Russulaceae (Lactarius volemus). Laccase was purified by using saturated precipitate (NH4)2SO4, DEAE-cellulose and immobilized on silica fume. Batch adsorption experiments have been performed as a function of pH, contact time, temperature and adsorbent dosage. The optimum results were obtained at pH 6, contact time of 60 min, temperature of 20 ºC and an adsorbent dose of 1 mg/mL. The Freundlich equation was found to have the highest value of R2 compared with the Langmuir model. Thermodynamic parameters including the Gibbs free energy, enthalpy and entropy changes indicated that the adsorption of Acid red 37 onto laccase-modified silica fume was feasible, spontaneous and endothermic. The results show that the laccase-modified silica fume can be used for the treatment of aqueous solutions as an alternative low cost adsorbent.
Purpouse: The Ames Salmonella/microsome mutagenicity assay is a short-term\nbacterial reverse mutation assay specifically designed to detect a wide range of\nchemical substances that can produce genetic damage that leads to gene mutations.\nMethods: In this study, we evaluated the mutagenic potential of a combinational\nprophylactic transdermal patches containing eserine and pralidoxime chloride (2-\nPAM) and its placebo patches using TA98, TA100, TA1535 and TA1538 strains of\nSalmonella typhimurium by Ames test. Characterization of the patches was done\nbefore the initiation of the study. The assays were performed according to the plate\nincorporation procedure described by Organization for Economic Cooperation and\nDevelopment (OECD) recommendations and Ames and Whitfield spot test procedure.\nResults: Both eserine and 2-PAM drugs impregnated patches along with drug\nunimpregnated patches were found to be not mutagenic. Conclusion: This\ninvestigation is of interest due to its pharmacological properties of these drugs.